JUUL delivers substantially more nicotine to the blood per puff than cigarettes or previous-generation e-cigarettes (e-cigs) and impairs blood vessel function comparable to cigarette smoke, according to a new study by re搜索ers at UC 旧金山.
A caveat of this study is that it measured the impact of equal numbers of puffs of all products, whereas adult former cigarette smokers may stop their vaping session when they reach the level of nicotine they normally ingest, said senior author 马修·斯普林格博士，加州大学旧金山分校心脏病学教授和成员的 UCSF中心烟草研究和教育.
The re搜索 found that blood nicotine concentrations in the JUUL group (136.4 ng/ml) was eight times higher than e-cigs group (17.1 ng/ml) and 5.2 times higher than cigarettes (26.1 ng/ml).
Our findings show that the adverse effect of cigarettes on vascular endothelial function, which has been a known consequence of cigarette smoking since the 1990s, is not prevented by using JUUL.
However, while Springer and his colleagues found that aerosol or smoke from JUUL caused greater blood vessel impairment than either of the other nicotine sources, the differences in the extent of impairment between the sources themselves was deemed statistically insignificant.
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The University of California, 旧金山 (UCSF) is exclusively focused on the health sciences and is dedicated to promoting health worldwide through advanced biomedical re搜索, graduate-level education in the life sciences and health professions, and excellence in patient care. UCSF医疗，其用作UCSF的主要学术医疗中心，包括 世界排名第一的专业医院 and other clinical programs, and has affiliations throughout the Bay Area.